Calreticulin

(Immune System)

Tech

skills
Immune System
Link to Dbpedia

What is Calreticulin?

Calreticulin also known as calregulin, CRP55, CaBP3, calsequestrin-like protein, and endoplasmic reticulum resident protein 60 (ERp60) is a protein that in humans is encoded by the CALR gene. Calreticulin is a multifunctional soluble protein that binds Ca2+ ions (a second messenger in signal transduction), rendering it inactive. The Ca2+ is bound with low affinity, but high capacity, and can be released on a signal (see inositol trisphosphate). Calreticulin is located in storage compartments associated with the endoplasmic reticulum and is considered an ER resident protein. The term "Mobilferrin" is considered to be the same as calreticulin by some sources.

Technology Types

biomoleculec-type lectinchemicalcompoundconjugated proteingeneglycoproteinhuman geneimmune systemlectinmacromoleculematerialmolecular chaperonemoleculeorganic compoundproteinsubstancetranscription coregulator

Synonyms

Autoantigen RoCaBP3CALRCalregulinCalsequestrin-like proteinCRP55Mobilferrin

Translations

Calreticulina (ca)Calréticuline (fr)Kalretikulin (cs)Кальретикулін (uk)

Tech Info

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 — Date merged: 11/6/2021, 1:33:00 PM
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